The interaction of host and nematode galectins influences the outcome of gastrointestinal nematode infections.
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SUBMITTER: Donskow-Lysoniewska K
PROVIDER: S-EPMC11010190 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
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The interaction of host and nematode galectins influences the outcome of gastrointestinal nematode infections.
Donskow-Łysoniewska Katarzyna K Maruszewska-Cheruiyot Marta M Stear Michael M
Parasitology 20210119 6
Galectins are a family of proteins that bind β-galactosides and play key roles in a variety of cellular processes including host defence. They have been well studied in hosts but less so in gastrointestinal nematodes. Both host and parasite galectins are present in the gastrointestinal tract following infection. Parasite galectins can both bind antibody, especially highly glycosylated IgE and be bound by antibody. Parasite galectins may act as molecular sponges that soak up antibody. Host galect ...[more]
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