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Establishment of animal models and behavioral studies for autism spectrum disorders.


ABSTRACT: In recent years, the incidence of autism spectrum disorder (ASD) has increased, but the etiology and pathogenesis remain unclear. In this narrative review, we review and systematically summarize the methods used to construct animal models to study ASD and the related behavioral studies based on recent literature. Utilization of various ASD animal models can complement research on the etiology, pathogenesis, and core behaviors of ASD, providing information and a foundation for further basic research and clinical treatment of ASD.

SUBMITTER: Jiao D 

PROVIDER: S-EPMC11022675 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature

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Establishment of animal models and behavioral studies for autism spectrum disorders.

Jiao Daiyan D   Xu Yingkai Y   Tian Fei F   Zhou Yaqing Y   Chen Dong D   Wang Yujue Y  

The Journal of international medical research 20240401 4


In recent years, the incidence of autism spectrum disorder (ASD) has increased, but the etiology and pathogenesis remain unclear. In this narrative review, we review and systematically summarize the methods used to construct animal models to study ASD and the related behavioral studies based on recent literature. Utilization of various ASD animal models can complement research on the etiology, pathogenesis, and core behaviors of ASD, providing information and a foundation for further basic resea  ...[more]

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