Ontology highlight
ABSTRACT:
SUBMITTER: Banks JD
PROVIDER: S-EPMC110434 | biostudies-literature | 1998 Jul
REPOSITORIES: biostudies-literature
Journal of virology 19980701 7
We have defined a 160-nucleotide region, Mpsi, from the 5' leader region of the Rous sarcoma virus genome that is sufficient to direct the packaging of a heterologous RNA. Mpsi contains the putative O3 stem structure that has previously been shown, and that has been confirmed in this study, to be important for the efficient packaging of avian leukosis-sarcoma virus RNA. Analyses of several O3 stem mutants revealed that other regions within Mpsi can interfere with the proper folding of altered se ...[more]