Ontology highlight
ABSTRACT:
SUBMITTER: Liang F
PROVIDER: S-EPMC110731 | biostudies-literature | 2000 Sep
REPOSITORIES: biostudies-literature
Liang F F Holt I I Pertea G G Karamycheva S S Salzberg S L SL Quackenbush J J
Nucleic acids research 20000901 18
The vast body of Expressed Sequence Tag (EST) data in the public databases provide an important resource for comparative and functional genomics studies and an invaluable tool for the annotation of genomic sequences. We have developed a rigorous protocol for reconstructing the sequences of transcribed genes from EST and gene sequence fragments. A key element in developing this protocol has been the evaluation of a number of sequence assembly programs to determine which most faithfully reproduce ...[more]