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Bacteriophage Mu targets the trinucleotide sequence CGG.


ABSTRACT: Target specificity for bacteriophage Mu was studied using a new phage derivative that enabled cloning of Mu-host junctions from phage DNA. Insertions distributed throughout the chromosome showed no orientation bias with respect to transcription or replication polarity. Genes with a high frequency of the triplet CGG were preferred targets.

SUBMITTER: Manna D 

PROVIDER: S-EPMC1112026 | biostudies-literature | 2005 May

REPOSITORIES: biostudies-literature

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Bacteriophage Mu targets the trinucleotide sequence CGG.

Manna Dipankar D   Deng Shuang S   Breier Adam M AM   Higgins N Patrick NP  

Journal of bacteriology 20050501 10


Target specificity for bacteriophage Mu was studied using a new phage derivative that enabled cloning of Mu-host junctions from phage DNA. Insertions distributed throughout the chromosome showed no orientation bias with respect to transcription or replication polarity. Genes with a high frequency of the triplet CGG were preferred targets. ...[more]

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