Ontology highlight
ABSTRACT:
SUBMITTER: Masaoka Y
PROVIDER: S-EPMC111282 | biostudies-literature | 2000 Apr
REPOSITORIES: biostudies-literature
Masaoka Y Y Ueno Y Y Morita Y Y Kuroda T T Mizushima T T Tsuchiya T T
Journal of bacteriology 20000401 8
Genes (ebrAB) responsible for ethidium resistance were cloned from chromosomal DNA of Bacillus subtilis ATCC 9372. The recombinant plasmid produced elevated resistance against ethidium bromide, acriflavine, pyronine Y, and safranin O not only in Escherichia coli but also in B. subtilis. It also caused an elevated energy-dependent efflux of ethidium in E. coli. EbrA and EbrB showed high sequence similarity with members of the small multidrug resistance (SMR) family of multidrug efflux pumps. Neit ...[more]