Role of motility in adherence to and invasion of a fish cell line by Vibrio anguillarum.
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ABSTRACT:
SUBMITTER: Ormonde P
PROVIDER: S-EPMC111286 | biostudies-literature | 2000 Apr
REPOSITORIES: biostudies-literature
Publications
Role of motility in adherence to and invasion of a fish cell line by Vibrio anguillarum.
Ormonde P P Hörstedt P P O'Toole R R Milton D L DL
Journal of bacteriology 20000401 8
To understand further the role of the flagellum of Vibrio anguillarum in virulence, invasive and adhesive properties of isogenic motility mutants were analyzed by using a chinook salmon embryo cell line. Adhesion was unaffected but invasion of the cell line was significantly decreased in nonmotile or partially motile mutants, and the chemotactic mutant was hyperinvasive. These results suggest that active motility aids invasion by V. anguillarum, both in vivo and in vitro. ...[more]
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