Ontology highlight
ABSTRACT:
SUBMITTER: Ha Y
PROVIDER: S-EPMC11233023 | biostudies-literature | 2024 Jun
REPOSITORIES: biostudies-literature
Ha Yuanchi Y Ma Helena R HR Wu Feilun F Weiss Andrea A Duncker Katherine K Xu Helen Z HZ Lu Jia J Golovsky Max M Reker Daniel D You Lingchong L
PLoS computational biology 20240603 6
Multi-factor screenings are commonly used in diverse applications in medicine and bioengineering, including optimizing combination drug treatments and microbiome engineering. Despite the advances in high-throughput technologies, large-scale experiments typically remain prohibitively expensive. Here we introduce a machine learning platform, structure-augmented regression (SAR), that exploits the intrinsic structure of each biological system to learn a high-accuracy model with minimal data require ...[more]