Ontology highlight
ABSTRACT:
SUBMITTER: Ebbah E
PROVIDER: S-EPMC11287735 | biostudies-literature | 2024 Jul
REPOSITORIES: biostudies-literature
Ebbah Eunice E Amissah Anthony A Kim Jun-Hyun JH Driskell Jeremy D JD
ACS sensors 20240624 7
Here, we describe a SERS-based vertical flow assay as a platform technology suitable for point-of-care (POC) diagnostic testing. A capture substrate is constructed from filter paper embedded with spherical gold nanoparticles (AuNPs) and functionalized with an appropriate capture antibody. The capture substrate is loaded into a filtration device and connected to a syringe to rapidly and repeatedly pass the sample through the sensor for efficient antigen binding. The antigen is then labeled with a ...[more]