Dataset Information

Strain assessment in patients with aortic regurgitation undergoing transcatheter aortic valve implantation: case series.

ABSTRACT:

Background

Limited data exist on strain changes after transcatheter aortic valve implantation (TAVI) in patients with aortic regurgitation (AR).

Case summary

Three patients with AR undergoing TAVI showed an initial reduction in global longitudinal strain (GLS), followed by sustained GLS improvement within the first year.

Discussion

Findings align with those of surgically treated patients with AR. There is a possible superiority of GLS to left ventricular end-diastolic diameter ratio in assessing patients with severe volume overload.

SUBMITTER: Bartkowiak J

PROVIDER: S-EPMC11303856 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Publications

Strain assessment in patients with aortic regurgitation undergoing transcatheter aortic valve implantation: case series.

Bartkowiak Joanna J Agarwal Vratika V Lebehn Mark M Nazif Tamim M TM George Isaac I Kodali Susheel K SK Vahl Torsten P TP Hahn Rebecca T RT

European heart journal. Case reports 20240705 8

<h4>Background</h4>Limited data exist on strain changes after transcatheter aortic valve implantation (TAVI) in patients with aortic regurgitation (AR).<h4>Case summary</h4>Three patients with AR undergoing TAVI showed an initial reduction in global longitudinal strain (GLS), followed by sustained GLS improvement within the first year.<h4>Discussion</h4>Findings align with those of surgically treated patients with AR. There is a possible superiority of GLS to left ventricular end-diastolic diame ...[more]

PMID: 39113778

Similar Datasets

Project description:Chronic silent brain infarctions, detected as new white matter hyperintensities on magnetic resonance imaging (MRI) following transcatheter aortic valve implantation (TAVI), are associated with long-term cognitive deterioration. This is the first study to investigate to which extent the calcification volume of the native aortic valve (AV) measured with cardiac computed tomography angiography (CTA) predicts the increase in chronic white matter hyperintensity volume after TAVI. A total of 36 patients (79 ± 5 years, median EuroSCORE II 1.9%, Q1-Q3 1.5-3.4%) with severe AV stenosis underwent fluid attenuation inversion recovery (FLAIR) MRI < 24 h prior to TAVI and at 3 months follow-up for assessment of cerebral white matter hyperintensity volume (mL). Calcification volumes (mm3) of the AV, aortic arch, landing zone and left ventricle were measured on the CTA pre-TAVI. The largest calcification volumes were found in the AV (median 692 mm3) and aortic arch (median 633 mm3), with a large variation between patients (Q1-Q3 482-1297 mm3 and 213-1727 mm3, respectively). The white matter hyperintensity volume increased in 72% of the patients. In these patients the median volume increase was of 1.1 mL (Q1-Q3 0.3-4.6 mL), corresponding with a 27% increase from baseline (Q1-Q3 7-104%). The calcification volume in the AV predicted the increase of white matter hyperintensity volume (Δ%), with a 35% increase of white matter hyperintensity volume, per 100 mm3 of AV calcification volume (SE 8.5, p < 0.001). The calcification volumes in the aortic arch, landing zone and left ventricle were not associated with the increase in white matter hyperintensity volume. In 72% of the patients new chronic white matter hyperintensities developed 3 months after TAVI, with a median increase of 27%. A higher calcification volume in the AV was associated with a larger increase in the white matter hyperintensity volume. These findings show the potential for automated AV calcium screening as an imaging biomarker to predict chronic silent brain infarctions.

Dataset Information

Strain assessment in patients with aortic regurgitation undergoing transcatheter aortic valve implantation: case series.

Background

Case summary

Discussion

Publications

Strain assessment in patients with aortic regurgitation undergoing transcatheter aortic valve implantation: case series.

Similar Datasets

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