Ontology highlight
ABSTRACT:
SUBMITTER: Bhattacharya S
PROVIDER: S-EPMC11308774 | biostudies-literature | 2024 Jul
REPOSITORIES: biostudies-literature
Bhattacharya Sonia S Jenkins Matthew C MC Keshavarz-Joud Parisa P Bourque Alisyn Retos AR White Keiyana K Alvarez Barkane Amina Maria AM Bryksin Anton V AV Hernandez Carolina C Kopylov Mykhailo M Finn M G MG
ACS nano 20240723
Protein nanoparticles are effective platforms for antigen presentation and targeting effector immune cells in vaccine development. Encapsulins are a class of protein-based microbial nanocompartments that self-assemble into icosahedral structures with external diameters ranging from 24 to 42 nm. Encapsulins from <i>Myxococcus xanthus</i> were designed to package bacterial RNA when produced in <i>E. coli</i> and were shown to have immunogenic and self-adjuvanting properties enhanced by this RNA. W ...[more]