Ontology highlight
ABSTRACT:
SUBMITTER: Phan T
PROVIDER: S-EPMC11309407 | biostudies-literature | 2024 Jul
REPOSITORIES: biostudies-literature
Phan Tin T Conway Jessica M JM Pagane Nicole N Kreig Jasmine J Sambaturu Narmada N Iyaniwura Sarafa S Li Jonathan Z JZ Ribeiro Ruy M RM Ke Ruian R Perelson Alan S AS
PLoS pathogens 20240729 7
Most people living with HIV-1 experience rapid viral rebound once antiretroviral therapy is interrupted; however, a small fraction remain in viral remission for an extended duration. Understanding the factors that determine whether viral rebound is likely after treatment interruption can enable the development of optimal treatment regimens and therapeutic interventions to potentially achieve a functional cure for HIV-1. We built upon the theoretical framework proposed by Conway and Perelson to c ...[more]