Ontology highlight
ABSTRACT:
SUBMITTER: Nitta M
PROVIDER: S-EPMC113144 | biostudies-literature | 2000 Nov
REPOSITORIES: biostudies-literature
Nitta M M Saijo M M Kodo N N Matsuda T T Nakatsu Y Y Tamai H H Tanaka K K
Nucleic acids research 20001101 21
The xeroderma pigmentosum group A protein (XPA) plays a central role in nucleotide excision repair (NER). To identify proteins that bind to XPA, we screened a HeLa cDNA library using the yeast two-hybrid system. Here we report a novel cytoplasmic GTP-binding protein, designated XPA binding protein 1 (XAB1). The deduced amino acid sequence of XAB1 consisted of 374 residues with a molecular weight of 41 kDa and an isoelectric point of 4.65. Sequence analysis revealed that XAB1 has four sequence mo ...[more]