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Understanding general practitioner and pharmacist preferences for pharmacogenetic testing in primary care: a discrete choice experiment.


ABSTRACT: Pharmacogenetic testing in the United Kingdom's National Health Service (NHS) has historically been reactive in nature, undertaken in the context of single gene-drug relationships in specialist settings. Using a discrete choice experiment we aimed to identify healthcare professional preferences for development of a pharmacogenetic testing service in primary care in the NHS. Respondents, representing two professions groups (general practitioners or pharmacists), completed one of two survey versions, asking them to select their preferred pharmacogenetic testing service in the context of a presentation of low mood or joint pain. Responses from 235 individuals were included. All respondents preferred pharmacogenetic testing over no testing, though preference heterogeneity was identified. Both professional groups, but especially GPs, were highly sensitive to service design, with uptake varying depending on the service offered. This study demonstrates uptake of a pharmacogenetic testing service is impacted by service design and highlights key areas which should be prioritised within future initiatives.

SUBMITTER: McDermott JH 

PROVIDER: S-EPMC11315669 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Understanding general practitioner and pharmacist preferences for pharmacogenetic testing in primary care: a discrete choice experiment.

McDermott John H JH   Sharma Videha V   Beaman Glenda M GM   Keen Jessica J   Newman William G WG   Wilson Paul P   Payne Katherine K   Wright Stuart S  

The pharmacogenomics journal 20240809 5


Pharmacogenetic testing in the United Kingdom's National Health Service (NHS) has historically been reactive in nature, undertaken in the context of single gene-drug relationships in specialist settings. Using a discrete choice experiment we aimed to identify healthcare professional preferences for development of a pharmacogenetic testing service in primary care in the NHS. Respondents, representing two professions groups (general practitioners or pharmacists), completed one of two survey versio  ...[more]

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