Ontology highlight
ABSTRACT:
SUBMITTER: McDonald ND
PROVIDER: S-EPMC11316592 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
McDonald Nathan D ND Antoshak Erin E EE
Access microbiology 20240717 7
Synthetic biology and genome engineering capabilities have facilitated the utilization of bacteria for a myriad of applications, ranging from medical treatments to biomanufacturing of complex molecules. The bacterial outer membrane, specifically the lipopolysaccharide (LPS), plays an integral role in the physiology, pathogenesis, and serves as a main target of existing detection assays for Gram-negative bacteria. Here we use CRISPR/Cas9 recombineering to insert <i>Yersinia pestis</i> lipid A bio ...[more]