Lower respiratory tract microbiome and lung cancer risk prediction in patients with diffuse lung parenchymal lesions.

ABSTRACT:

Objective

In clinical practice, imaging manifestations of diffuse lung parenchymal lesions are common and indicative of various diseases, making differential diagnosis difficult. Some of these lesions are eventually diagnosed as lung cancer.

Methods

Because respiratory microorganisms play an important role in lung cancer development, we searched for microbial markers that could predict the risk of lung cancer by retrospectively analyzing the lower respiratory tract (LRT) microbiome of 158 patients who were hospitalized in the First Affiliated Hospital of Guangzhou Medical University (March 2021-March 2023) with diffuse lung parenchymal lesions. The final diagnosis was lung cancer in 21 cases, lung infection in 93 cases, and other conditions (other than malignancy and infecti

SUBMITTER: Wang X 

PROVIDER: S-EPMC11341542 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature