Ontology highlight
ABSTRACT:
SUBMITTER: Wekema L
PROVIDER: S-EPMC11354285 | biostudies-literature | 2024 Aug
REPOSITORIES: biostudies-literature
Wekema Lieske L Schoenmakers Sam S Schenkelaars Nicole N Laskewitz Anne A Huurman Romy H RH Liu Lei L Walters Lisa L Harmsen Hermie J M HJM Steegers-Theunissen Régine P M RPM Faas Marijke M MM
International journal of molecular sciences 20240821 16
Maternal obesity during pregnancy is associated with adverse pregnancy outcomes. This might be due to undesired obesity-induced changes in the maternal gut microbiota and related changes in the maternal immune adaptations during pregnancy. The current study examines how obesity affects gut microbiota and immunity in pregnant obese and lean mice during mid-pregnancy (gestational day 12 (GD12)). C57BL/6 mice were fed a high-fat diet or low-fat diet from 8 weeks before mating and during pregnancy. ...[more]