Dataset Information

Post-discharge functional outcomes in older patients with sepsis.

ABSTRACT:

Background

The post-discharge prognosis of patients with sepsis remains a crucial issue; however, few studies have investigated the relationship between pre-sepsis health status and subsequent prognosis in a large population. This study aimed to examine the effect of the pre-sepsis care needs level on changes in care needs and mortality in patients with sepsis 1 year post-discharge.

Methods

This was a population-based retrospective cohort study including twelve municipalities in Japan that participated in the Longevity Improvement & Fair Evidence study between April 2014 and March 2022, with a total of 1,491,608 persons. The pre-hospitalization levels of care needs (baseline) were classified from low to high, as no care needs, support level and care needs level 1, care needs levels 2-3, and care needs levels 4-5 (fully dependent). The outcomes were changes in care needs level and mortality 1 year post-discharge, assessed by baseline care needs level using Cox proportional hazard models.

Results

The care needs levels of 17,648 patients analyzed at baseline were as follows: no care needs, 7982 (45.2%); support level and care needs level 1, 3736 (21.2%); care needs levels 2-3, 3089 (17.5%); and care needs levels 4-5, 2841 (16.1%). At 1 year post-discharge, the distribution of care needs were as follows: no care needs, 4791 (27.1%); support level and care needs level 1, 2390 (13.5%); care needs levels 2-3, 2629 (14.9%); care needs levels 4-5, 3373 (19.1%); and death, 4465 (25.3%). Patients with higher levels of care needs exhibited an increased association of all-cause mortality 1 year post-discharge after adjusting for confounders [hazard ratios and 95% confidence intervals: support level and care needs level 1, 1.05 (0.96, 1.15); care needs levels 2-3, 1.46 (1.33, 1.60); and care needs levels 4-5, 1.92 (1.75, 2.10); P for trend < 0.001].

Conclusions

Elevated care needs and mortality were observed in patients with sepsis within 1 year post-discharge. Older patients with sepsis and higher baseline levels of care needs had a high association of all-cause mortality 1 year post-discharge.

SUBMITTER: Ge S

PROVIDER: S-EPMC11363546 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Publications

Post-discharge functional outcomes in older patients with sepsis.

Ge Sanyu S Zha Ling L Tanaka Aiko A Narii Nobuhiro N Shimomura Yoshimitsu Y Komatsu Masayo M Komukai Sho S Murata Fumiko F Maeda Megumi M Kiyohara Kosuke K Kitamura Tetsuhisa T Fukuda Haruhisa H

Critical care (London, England) 20240829 1

<h4>Background</h4>The post-discharge prognosis of patients with sepsis remains a crucial issue; however, few studies have investigated the relationship between pre-sepsis health status and subsequent prognosis in a large population. This study aimed to examine the effect of the pre-sepsis care needs level on changes in care needs and mortality in patients with sepsis 1 year post-discharge.<h4>Methods</h4>This was a population-based retrospective cohort study including twelve municipalities in J ...[more]

PMID: 39210369

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Dataset Information

Post-discharge functional outcomes in older patients with sepsis.

Background

Methods

Results

Conclusions

Publications

Post-discharge functional outcomes in older patients with sepsis.

Similar Datasets

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