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ABSTRACT: Objective
To assess the quantity and focus of recent empirical research regarding the effect of micronutrient supplementation on live birth outcomes in low-risk pregnancies from high-income countries.Design
A systematic quantitative literature review.Setting
Low-risk pregnancies in World Bank-classified high-income countries, 2019.Results
Using carefully selected search criteria, a total of 2475 publications were identified, of which seventeen papers met the inclusion criteria for this review. Data contributing to nine of the studies were sourced from four cohorts; research originated from ten countries. These cohorts exhibited a large number of participants, stable data and a low probability of bias. The most recent empirical data offered by these studies was 2011; the most historical was 1980. In total, fifty-five categorical outcome/supplement combinations were examined; 67·3 % reported no evidence of micronutrient supplementation influencing selected outcomes.Conclusions
A coordinated, cohesive and uniform empirical approach to future studies is required to determine what constitutes appropriate, effective and safe micronutrient supplementation in contemporary cohorts from high-income countries, and how this might influence pregnancy outcomes.
SUBMITTER: James-McAlpine JM
PROVIDER: S-EPMC11374547 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
James-McAlpine Janelle M JM Vincze Lisa L Vanderlelie Jessica J JJ Perkins Anthony V AV
Public health nutrition 20200609 13
<h4>Objective</h4>To assess the quantity and focus of recent empirical research regarding the effect of micronutrient supplementation on live birth outcomes in low-risk pregnancies from high-income countries.<h4>Design</h4>A systematic quantitative literature review.<h4>Setting</h4>Low-risk pregnancies in World Bank-classified high-income countries, 2019.<h4>Results</h4>Using carefully selected search criteria, a total of 2475 publications were identified, of which seventeen papers met the inclu ...[more]