Isolation and expression of a novel molecular class D beta-lactamase, OXA-61, from Campylobacter jejuni.
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ABSTRACT:
SUBMITTER: Alfredson DA
PROVIDER: S-EPMC1140520 | biostudies-literature | 2005 Jun
REPOSITORIES: biostudies-literature
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Isolation and expression of a novel molecular class D beta-lactamase, OXA-61, from Campylobacter jejuni.
Alfredson David A DA Korolik Victoria V
Antimicrobial agents and chemotherapy 20050601 6
A novel beta-lactamase gene, blaOXA-61, from Campylobacter jejuni GC015 was cloned and its nucleotide sequence determined. blaOXA-61 encodes a protein of 257 amino acids in which the active-site STFK tetrad and conserved class D beta-lactamase motifs YGN and KTG were identified. A conserved sequence upstream of blaOXA-61 is required for expression in Campylobacter. ...[more]
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