Ontology highlight
ABSTRACT:
SUBMITTER: Rietsch A
PROVIDER: S-EPMC1142391 | biostudies-literature | 2005 May
REPOSITORIES: biostudies-literature
Rietsch Arne A Vallet-Gely Isabelle I Dove Simon L SL Mekalanos John J JJ
Proceedings of the National Academy of Sciences of the United States of America 20050523 22
Type III secretion systems are toxin delivery systems that are present in a large number of pathogens. A hallmark of all type III secretion systems studied to date is that expression of one or more of their components is induced upon cell contact. It has been proposed that this induction is controlled by a negative regulator that is itself secreted by means of the type III secretion machinery. Although candidate proteins for this negative regulator have been proposed in a number of systems, for ...[more]