Ontology highlight
ABSTRACT:
SUBMITTER: Chia CP
PROVIDER: S-EPMC1142416 | biostudies-literature | 2005 Jun
REPOSITORIES: biostudies-literature
Chia Catherine P CP Gomathinayagam Sujatha S Schmaltz Robert J RJ Smoyer Laura K LK
Molecular biology of the cell 20050323 6
Glycoprotein gp130, found on the plasma membrane of Dictyostelium discoideum amoebae, was postulated previously to play a role in phagocytosis. The gene for gp130 was cloned and when translated, yielded a 768 amino acid preproprotein of 85.3 kDa. It had nearly 40% similarity to the 138 kDa family of glycoproteins implicated in sexual cell fusion during macrocyst formation in D. discoideum. The difference between the calculated size and observed M(r) of 130 kDa on protein gels likely was due to N ...[more]