Ontology highlight
ABSTRACT:
SUBMITTER: Islam SA
PROVIDER: S-EPMC114246 | biostudies-literature | 2001 May
REPOSITORIES: biostudies-literature
Islam S A SA Hay C M CM Hartman K E KE He S S Shea A K AK Trocha A K AK Dynan M J MJ Reshamwala N N Buchbinder S P SP Basgoz N O NO Kalams S A SA
Journal of virology 20010501 10
We longitudinally measured T-cell receptor transcript frequencies of human immunodeficiency virus type 1 (HIV-1) specific cytotoxic T lymphocytes (CTL) in an individual with rapidly progressive disease and high levels of viremia. CTL clones elicited during acute HIV-1 infection were present at the time of death, despite absent functional CTL responses, arguing against clonal deletion as a mechanism for the decline of CTL responses observed during HIV-1 infection. ...[more]