Segregation of EAV-HP ancient endogenous retroviruses within the chicken population.
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ABSTRACT:
SUBMITTER: Sacco MA
PROVIDER: S-EPMC114785 | biostudies-literature | 2001 Dec
REPOSITORIES: biostudies-literature
Publications
Segregation of EAV-HP ancient endogenous retroviruses within the chicken population.
Journal of virology 20011201 23
Avian leukosis virus subgroup J (ALV-J), an exogenous avian retrovirus, is thought to have evolved by recombination with the highly identical env gene of the endogenous avian retrovirus EAV-HP. Embryonic expression of EAV-HP env has been suggested to be associated with the induction of immunological tolerance, a feature observed in a significant proportion of meat-type chickens infected with ALV-J. In support of this hypothesis, we demonstrate that EAV-HP loci, some of which could be associated ...[more]
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