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Glutamine synthesis is essential for growth of Streptococcus thermophilus in milk and is linked to urea catabolism.


ABSTRACT: Growth of a glutamine synthetase-deficient mutant of Streptococcus thermophilus was compared to that of the parent strain in milk that was not supplemented or was supplemented with ammonium chloride, glutamine, or the urease inhibitor flurofamide. It was concluded that one of the functions of urease is to supply ammonia for the synthesis of glutamine.

SUBMITTER: Monnet C 

PROVIDER: S-EPMC1151851 | biostudies-literature | 2005 Jun

REPOSITORIES: biostudies-literature

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Glutamine synthesis is essential for growth of Streptococcus thermophilus in milk and is linked to urea catabolism.

Monnet Christophe C   Mora Diego D   Corrieu Georges G  

Applied and environmental microbiology 20050601 6


Growth of a glutamine synthetase-deficient mutant of Streptococcus thermophilus was compared to that of the parent strain in milk that was not supplemented or was supplemented with ammonium chloride, glutamine, or the urease inhibitor flurofamide. It was concluded that one of the functions of urease is to supply ammonia for the synthesis of glutamine. ...[more]

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