Depressive symptoms profile and dementia risk after spontaneous intracerebral haemorrhage.

ABSTRACT:

Introduction

Depressive symptoms are commonly reported after spontaneous intracerebral haemorrhage (ICH) and frequently associated with cognitive decline. Using hierarchical clustering analysis (HCA), we aimed to identify different post-ICH depressive symptoms profiles and to evaluate their association with dementia risk.

Methods

We included consecutive patients from the prospective Prognosis of Intracerebral Haemorrhage (PITCH) study who survived 6 months after the ICH. We performed HCA using depressive symptoms severity (assessed using the Montgomery-Åsberg Depression Rating Scale (MADRS)), along with the presence of apathy and anxiety (screened using Neuropsychiatric Inventory questionnaire). Baseline clinical/neuroimaging characteristics and risk of incident dementia wer

SUBMITTER: Scopelliti G 

PROVIDER: S-EPMC11556666 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature