Protein-DNA binding and CpG methylation at nucleotide resolution of latency-associated promoters Qp, Cp, and LMP1p of Epstein-Barr virus.
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ABSTRACT:
SUBMITTER: Salamon D
PROVIDER: S-EPMC115881 | biostudies-literature | 2001 Mar
REPOSITORIES: biostudies-literature
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Protein-DNA binding and CpG methylation at nucleotide resolution of latency-associated promoters Qp, Cp, and LMP1p of Epstein-Barr virus.
Salamon D D Takacs M M Ujvari D D Uhlig J J Wolf H H Minarovits J J Niller H H HH
Journal of virology 20010301 6
Epstein-Barr viral (EBV) latency-associated promoters Qp, Cp, and LMP1p are crucial for the regulated expression of the EBNA and LMP transcripts in dependence of the latency type. By transient transfection and in vitro binding analyses, many promoter elements and transcription factors have previously been shown to be involved in the activities of these promoters. However, the latency promoters have only partially been examined at the nucleotide level in vivo. Therefore, we undertook a comprehens ...[more]
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