Ontology highlight
ABSTRACT:
SUBMITTER: Garrow AG
PROVIDER: S-EPMC1160145 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Nucleic acids research 20050701 Web Server issue
TMB-Hunt is a program that uses a modified k-nearest neighbour (k-NN) algorithm to classify protein sequences as transmembrane beta-barrel (TMB) or non-TMB on the basis of whole sequence amino acid composition. By including differentially weighted amino acids, evolutionary information and by calibrating the scoring, a discrimination accuracy of 92.5% was achieved, as tested using a rigorous cross-validation procedure. The TMB-Hunt web server, available at www.bioinformatics.leeds.ac.uk/betaBarre ...[more]