Involvement of streptococcal mitogenic exotoxin Z in streptococcal toxic shock syndrome.
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ABSTRACT:
SUBMITTER: Yang L
PROVIDER: S-EPMC1169092 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
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Involvement of streptococcal mitogenic exotoxin Z in streptococcal toxic shock syndrome.
Yang Lily L Thomas Mark M Woodhouse Andrew A Martin Diana D Fraser John D JD Proft Thomas T
Journal of clinical microbiology 20050701 7
We report a nonfatal case of streptococcal toxic shock syndrome (STSS) caused by a Streptococcus pyogenes emm118 strain encoding a novel variant of streptococcal mitogenic exotoxin Z (SMEZ-34). This variant was responsible for the major mitogenic activity in the cell culture supernatant. Patient sera showed seroconversion toward SMEZ, implying a role for this toxin in STSS. ...[more]
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