Identification of unique bacterial gene segments from Streptococcus mutans with potential relevance to dental caries by subtraction DNA hybridization.
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ABSTRACT:
SUBMITTER: Saxena D
PROVIDER: S-EPMC1169107 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Publications
Identification of unique bacterial gene segments from Streptococcus mutans with potential relevance to dental caries by subtraction DNA hybridization.
Saxena Deepak D Li Yihong Y Caufield Page W PW
Journal of clinical microbiology 20050701 7
Using DNA subtractive hybridization, 49 unique gene segments were identified from a strain of Streptococcus mutans that was isolated from a patient with severe early childhood caries (S-ECC). Further hybridization with DNA from other S. mutans strains isolated from both caries-active and caries-free subjects yielded five unique sequences of DNA common to strains associated with S-ECC. ...[more]
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