Ontology highlight
ABSTRACT:
SUBMITTER: Meacci F
PROVIDER: S-EPMC1169130 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Meacci Francesca F Orrù Germano G Iona Elisabetta E Giannoni Federico F Piersimoni Claudio C Pozzi Gianni G Fattorini Lanfranco L Oggioni Marco R MR
Journal of clinical microbiology 20050701 7
The emergence and spread of multidrug-resistant (MDR) Mycobacterium tuberculosis (MT) represents a worldwide health care problem because of the difficulty in treating these infections. Development of drug resistance in MT arises mainly by mutation of chromosomal genes. To investigate the evolution of a MT population during a long-lasting infection, the phenotypic and genotypic changes in the drug resistance of 10 sequential MT isolates from a noncompliant chronically infected patient were invest ...[more]