Ontology highlight
ABSTRACT:
SUBMITTER: Gollmick FA
PROVIDER: S-EPMC117287 | biostudies-literature | 2002 Jun
REPOSITORIES: biostudies-literature
Gollmick Friedrich A FA Lorenz Mike M Dornberger Utz U von Langen Johannes J Diekmann Stephan S Fritzsche Hartmut H
Nucleic acids research 20020601 12
The NMR structure analysis is described for two DNA molecules of identical stem sequences with a five base loop containing a pyrimidine, thymin or uracil, in between purines. These five unpaired nucleotides are bulged out and are known to induce a kink in the duplex structure. The dAATAA bulge DNA is kinked between the third and the fourth nucleotide. This contrasts with the previously studied dAAAAA bulge DNA where we found a kink between the fourth and fifth nucleotide. The total kinking angle ...[more]