Ontology highlight
ABSTRACT:
SUBMITTER: Kempeneers V
PROVIDER: S-EPMC1175020 | biostudies-literature | 2005
REPOSITORIES: biostudies-literature
Kempeneers Veerle V Renders Marleen M Froeyen Matheus M Herdewijn Piet P
Nucleic acids research 20050712 12
DNA polymerases from different evolutionary families [Vent (exo-) DNA polymerase from the B-family polymerases, Taq DNA polymerase from the A-family polymerases and HIV reverse transcriptase from the reverse transcriptase family] were examined for their ability to incorporate the sugar-modified cyclohexenyl nucleoside triphosphates. All enzymes were able to use the cyclohexenyl nucleotides as a substrate. Using Vent (exo-) DNA polymerase and HIV reverse transcriptase, we were even able to incorp ...[more]