Ontology highlight
ABSTRACT:
SUBMITTER: O'Brien EK
PROVIDER: S-EPMC1180313 | biostudies-literature | 2003 Jun
REPOSITORIES: biostudies-literature
O'Brien Erin K EK Zhang Xuyang X Nishimura Carla C Tomblin J Bruce JB Murray Jeffrey C JC
American journal of human genetics 20030429 6
FOXP2 (forkhead box P2) was the first gene characterized in which a mutation affects human speech and language abilities. A common developmental language disorder, specific language impairment (SLI), affects 6%-7% of children with normal nonverbal intelligence and has evidence of a genetic basis in familial and twin studies. FOXP2 is located on chromosome 7q31, and studies of other disorders with speech and language impairment, including autism, have found linkage to this region. In the present ...[more]