Ontology highlight
ABSTRACT:
SUBMITTER: Fain PR
PROVIDER: S-EPMC1180316 | biostudies-literature | 2003 Jun
REPOSITORIES: biostudies-literature
Fain Pamela R PR Gowan Katherine K LaBerge Greggory S GS Alkhateeb Asem A Stetler Gary L GL Talbert Janet J Bennett Dorothy C DC Spritz Richard A RA
American journal of human genetics 20030418 6
Generalized vitiligo is a common autoimmune disorder characterized by the development of white patches of skin and overlying hair due to loss of pigment-forming melanocytes from the involved areas. Family clustering of cases is not uncommon, in a pattern suggestive of multifactorial, polygenic inheritance, and there is strong association between vitiligo and other autoimmune diseases. To map genetic loci that confer susceptibility to generalized vitiligo and perhaps other autoimmune diseases, we ...[more]