Ontology highlight
ABSTRACT:
SUBMITTER: Gilad Y
PROVIDER: S-EPMC1180675 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
Gilad Yoav Y Bustamante Carlos D CD Lancet Doron D Pääbo Svante S
American journal of human genetics 20030807 3
The olfactory receptor (OR) genes constitute the largest gene family in mammalian genomes. Humans have >1,000 OR genes, of which only approximately 40% have an intact coding region and are therefore putatively functional. In contrast, the fraction of intact OR genes in the genomes of the great apes is significantly greater (68%-72%), suggesting that selective pressures on the OR repertoire vary among these species. We have examined the evolutionary forces that shaped the OR gene family in humans ...[more]