Ontology highlight
ABSTRACT:
SUBMITTER: Walsh EC
PROVIDER: S-EPMC1180682 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
Walsh Emily C EC Mather Kristie A KA Schaffner Stephen F SF Farwell Lisa L Daly Mark J MJ Patterson Nick N Cullen Michael M Carrington Mary M Bugawan Teodorica L TL Erlich Henry H Campbell Jay J Barrett Jeffrey J Miller Katie K Thomson Glenys G Lander Eric S ES Rioux John D JD
American journal of human genetics 20030814 3
Numerous studies have clearly indicated a role for the major histocompatibility complex (MHC) in susceptibility to autoimmune diseases. Such studies have focused on the genetic variation of a small number of classical human-leukocyte-antigen (HLA) genes in the region. Although these genes represent good candidates, given their immunological roles, linkage disequilibrium (LD) surrounding these genes has made it difficult to rule out neighboring genes, many with immune function, as influencing dis ...[more]