Ontology highlight
ABSTRACT:
SUBMITTER: Hinds DA
PROVIDER: S-EPMC1181929 | biostudies-literature | 2004 Feb
REPOSITORIES: biostudies-literature
Hinds David A DA Stokowski Renee P RP Patil Nila N Konvicka Karel K Kershenobich David D Cox David R DR Ballinger Dennis G DG
American journal of human genetics 20040121 2
Association studies in populations that are genetically heterogeneous can yield large numbers of spurious associations if population subgroups are unequally represented among cases and controls. This problem is particularly acute for studies involving pooled genotyping of very large numbers of single-nucleotide-polymorphism (SNP) markers, because most methods for analysis of association in structured populations require individual genotyping data. In this study, we present several strategies for ...[more]