Ontology highlight
ABSTRACT:
SUBMITTER: Hodgkinson CA
PROVIDER: S-EPMC1182115 | biostudies-literature | 2004 Nov
REPOSITORIES: biostudies-literature
Hodgkinson Colin A CA Goldman David D Jaeger Judith J Persaud Shalini S Kane John M JM Lipsky Robert H RH Malhotra Anil K AK
American journal of human genetics 20040922 5
Schizophrenia, schizoaffective disorder, and bipolar disorder are common psychiatric disorders with high heritabilities and variable phenotypes. The Disrupted in Schizophrenia 1 (DISC1) gene, on chromosome 1q42, was originally discovered and linked to schizophrenia in a Scottish kindred carrying a balanced translocation that disrupts DISC1 and DISC2. More recently, DISC1 was linked to schizophrenia, broadly defined, in the general Finnish population, through the undertransmission to affected wom ...[more]