Association between initial antibiotic route and outcomes for children hospitalized with pneumonia.

ABSTRACT:

Background

Initial oral antibiotics may be as effective as intravenous (IV) antibiotics for children hospitalized with community-acquired pneumonia (CAP), but further data are needed.

Objective

We evaluated for associations of initial antibiotic route (IV vs. oral) with length of stay (LOS) and secondary outcomes for children hospitalized with CAP.

Methods

This multicenter, retrospective cohort study included children with CAP who were hospitalized for >48 h, had chest radiographs, and received antibiotics at four children's hospitals between 2014 and 2020. Data were obtained from the Pediatric Health Information System and manual chart review. The exposure was initial antibiotic route (i.e., first antibiotic given intravenously or orally). We performed multivariable

SUBMITTER: Cotter JM 

PROVIDER: S-EPMC11875966 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature