Ontology highlight
ABSTRACT:
SUBMITTER: Steiner P
PROVIDER: S-EPMC1187940 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Steiner Pascal P Alberi Stefano S Kulangara Karina K Yersin Alexandre A Sarria Juan-Carlos Floyd JC Regulier Etienne E Kasas Sandor S Dietler Giovanni G Muller Dominique D Catsicas Stefan S Hirling Harald H
The EMBO journal 20050721 16
Trafficking of AMPA-type glutamate receptors (AMPAR) between endosomes and the postsynaptic plasma membrane of neurons plays a central role in the control of synaptic strength associated with learning and memory. The molecular mechanisms of its regulation remain poorly understood, however. Here we show by biochemical and atomic force microscopy analyses that NEEP21, a neuronal endosomal protein necessary for receptor recycling including AMPAR, is associated with the scaffolding protein GRIP1 and ...[more]