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Characterization of the Vibrio cholerae vceCAB multiple-drug resistance efflux operon in Escherichia coli.


ABSTRACT: Herein, we identify vceC as a component of a vceCAB operon, which codes for the Vibrio cholerae VceAB multiple-drug resistance (MDR) efflux pump, and vceR, which codes for a transcriptional autoregulatory protein that negatively regulates the expression of the vceCAB operon and is modulated by some of the substrates of this MDR efflux pump.

SUBMITTER: Woolley RC 

PROVIDER: S-EPMC1196037 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature

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Characterization of the Vibrio cholerae vceCAB multiple-drug resistance efflux operon in Escherichia coli.

Woolley Robin C RC   Vediyappan Govindsamy G   Anderson Matthew M   Lackey Melinda M   Ramasubramanian Bhagavathi B   Jiangping Bai B   Borisova Tatyana T   Colmer Jane A JA   Hamood Abdul N AN   McVay Catherine S CS   Fralick Joe A JA  

Journal of bacteriology 20050801 15


Herein, we identify vceC as a component of a vceCAB operon, which codes for the Vibrio cholerae VceAB multiple-drug resistance (MDR) efflux pump, and vceR, which codes for a transcriptional autoregulatory protein that negatively regulates the expression of the vceCAB operon and is modulated by some of the substrates of this MDR efflux pump. ...[more]

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