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Xanthomonas campestris pv. campestris possesses a single gluconeogenic pathway that is required for virulence.


ABSTRACT: Disruption of ppsA, a key gene in gluconeogenesis, of Xanthomonas campestris pv. campestris resulted in the failure of the pathogen to grow in medium with pyruvate or C4-dicarboxylates as the sole carbon source and a significant reduction in virulence, indicating that X. campestris pv. campestris possesses only the malic enzyme-PpsA route in gluconeogenesis, which is required for virulence.

SUBMITTER: Tang DJ 

PROVIDER: S-EPMC1196132 | biostudies-literature | 2005 Sep

REPOSITORIES: biostudies-literature

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Xanthomonas campestris pv. campestris possesses a single gluconeogenic pathway that is required for virulence.

Tang Dong-Jie DJ   He Yong-Qiang YQ   Feng Jia-Xun JX   He Bao-Ren BR   Jiang Bo-Le BL   Lu Guang-Tao GT   Chen Baoshan B   Tang Ji-Liang JL  

Journal of bacteriology 20050901 17


Disruption of ppsA, a key gene in gluconeogenesis, of Xanthomonas campestris pv. campestris resulted in the failure of the pathogen to grow in medium with pyruvate or C4-dicarboxylates as the sole carbon source and a significant reduction in virulence, indicating that X. campestris pv. campestris possesses only the malic enzyme-PpsA route in gluconeogenesis, which is required for virulence. ...[more]

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