IS26-associated In4-type integrons forming multiresistance loci in enterobacterial plasmids.
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ABSTRACT:
SUBMITTER: Miriagou V
PROVIDER: S-EPMC1196216 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
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IS26-associated In4-type integrons forming multiresistance loci in enterobacterial plasmids.
Miriagou Vivi V Carattoli Alessandra A Tzelepi Eva E Villa Laura L Tzouvelekis Leonidas S LS
Antimicrobial agents and chemotherapy 20050801 8
Three distinct multiresistant loci from enterobacterial plasmids each comprised an integron and an IS26-associated sequence. Sequence comparison suggested a common ancestral structure that derived from an IS26 insertion into the 5' conserved segment of an In4-type integron and evolved through acquisition of gene cassettes and IS26-mediated recruitment of additional resistance genes of diverse origin. ...[more]
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