Origin of plasmid-mediated quinolone resistance determinant QnrA.
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ABSTRACT:
SUBMITTER: Poirel L
PROVIDER: S-EPMC1196254 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
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Origin of plasmid-mediated quinolone resistance determinant QnrA.
Poirel Laurent L Rodriguez-Martinez Jose-Manuel JM Mammeri Hedi H Liard Alain A Nordmann Patrice P
Antimicrobial agents and chemotherapy 20050801 8
Plasmid-mediated resistance to quinolones is increasingly reported in studies of Enterobacteriaceae. Using a PCR-based strategy, a series of gram-negative species were screened for qnrA-like genes. Shewanella algae, an environmental species from marine and fresh water, was identified as its reservoir. This is a one of the very few examples of progenitor identification of an acquired antibiotic resistance gene. ...[more]
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