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Origin of plasmid-mediated quinolone resistance determinant QnrA.


ABSTRACT: Plasmid-mediated resistance to quinolones is increasingly reported in studies of Enterobacteriaceae. Using a PCR-based strategy, a series of gram-negative species were screened for qnrA-like genes. Shewanella algae, an environmental species from marine and fresh water, was identified as its reservoir. This is a one of the very few examples of progenitor identification of an acquired antibiotic resistance gene.

SUBMITTER: Poirel L 

PROVIDER: S-EPMC1196254 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature

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Origin of plasmid-mediated quinolone resistance determinant QnrA.

Poirel Laurent L   Rodriguez-Martinez Jose-Manuel JM   Mammeri Hedi H   Liard Alain A   Nordmann Patrice P  

Antimicrobial agents and chemotherapy 20050801 8


Plasmid-mediated resistance to quinolones is increasingly reported in studies of Enterobacteriaceae. Using a PCR-based strategy, a series of gram-negative species were screened for qnrA-like genes. Shewanella algae, an environmental species from marine and fresh water, was identified as its reservoir. This is a one of the very few examples of progenitor identification of an acquired antibiotic resistance gene. ...[more]

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