Ontology highlight
ABSTRACT:
SUBMITTER: Moser MJ
PROVIDER: S-EPMC1196292 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Moser Michael J MJ Ruckstuhl Meta M Larsen Christine A CA Swearingen Amanda J AJ Kozlowski Miroslaw M Bassit Leda L Sharma Prem L PL Schinazi Raymond F RF Prudent James R JR
Antimicrobial agents and chemotherapy 20050801 8
In order to survive prolonged treatment with antiretroviral nucleoside analogs, the human immunodeficiency virus type 1 (HIV-1) is selectively forced to acquire mutations in the reverse transcriptase (RT) gene. Some of these mutations are more common than others and have become markers for antiretroviral resistance. For the early detection of these markers, a novel MultiCode-RTx one-step testing system to rapidly and simultaneously characterize mixtures of HIV-1 targets was designed. For cDNA, n ...[more]