Ontology highlight
ABSTRACT:
SUBMITTER: Bullard B
PROVIDER: S-EPMC1201204 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Bullard Brian B Lipski Serena L SL Lafontaine Eric R ER
Infection and immunity 20050801 8
Moraxella catarrhalis is a human pathogen that causes otitis media in young children and lung infections in patients with chronic obstructive pulmonary disease. In this study, the role of the surface protein Hag in the adherence of multiple M. catarrhalis strains was examined. The hag genes of four clinical isolates were disrupted with a spectinomycin resistance cassette, and the binding of isogenic mutants to primary cultures of human middle ear epithelial cells (HMEE), as well as A549 pneumocy ...[more]