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Isolation from a healthy carrier and characterization of a Neisseria meningitidis strain that is deficient in gamma-Glutamyl aminopeptidase activity.

ABSTRACT: gamma-Glutamyl aminopeptidase (GGT) activity is used as a specific marker for the identification of Neisseria meningitidis. We isolated from a healthy carrier and characterized an N. meningitidis isolate which lacked the activity due to the insertional mutation of the ggt gene, suggesting that naturally occurring N. meningitidis isolates do not always possess GGT activity.

SUBMITTER: Takahashi H 

PROVIDER: S-EPMC120689 | biostudies-literature | 2002 Aug

REPOSITORIES: biostudies-literature

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Isolation from a healthy carrier and characterization of a Neisseria meningitidis strain that is deficient in gamma-Glutamyl aminopeptidase activity.

Takahashi Hideyuki H   Tanaka Hiroshi H   Inouye Hiroo H   Kuroki Toshiro T   Watanabe Yuko Y   Yamai Shiro S   Watanabe Haruo H  

Journal of clinical microbiology 20020801 8

gamma-Glutamyl aminopeptidase (GGT) activity is used as a specific marker for the identification of Neisseria meningitidis. We isolated from a healthy carrier and characterized an N. meningitidis isolate which lacked the activity due to the insertional mutation of the ggt gene, suggesting that naturally occurring N. meningitidis isolates do not always possess GGT activity. ...[more]

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