Biosynthesis of natural flavanones in Saccharomyces cerevisiae.
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ABSTRACT:
SUBMITTER: Yan Y
PROVIDER: S-EPMC1214632 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
Publications
Biosynthesis of natural flavanones in Saccharomyces cerevisiae.
Yan Yajun Y Kohli Abhijeet A Koffas Mattheos A G MA
Applied and environmental microbiology 20050901 9
A four-step flavanone biosynthetic pathway was constructed and introduced into Saccharomyces cerevisiae. The recombinant yeast strain was fed with phenylpropanoid acids and produced the flavanones naringenin and pinocembrin 62 and 22 times more efficiently compared to previously reported recombinant prokaryotic strains. Microbial biosynthesis of the flavanone eriodictyol was also achieved. ...[more]
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