Disintegration of Staphylococcus epidermidis biofilms under glucose-limiting conditions depends on the activity of the alternative sigma factor sigmaB.
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ABSTRACT:
SUBMITTER: Jager S
PROVIDER: S-EPMC1214654 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
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Disintegration of Staphylococcus epidermidis biofilms under glucose-limiting conditions depends on the activity of the alternative sigma factor sigmaB.
Jäger Sebastian S Mack Dietrich D Rohde Holger H Horstkotte Matthias A MA Knobloch Johannes K-M JK
Applied and environmental microbiology 20050901 9
To evaluate the role of the polysaccharide intercellular adhesin as an energy-storage molecule, we investigated the effect of nutrient limitation on S. epidermidis biofilms. The stability of established biofilms depends on sigma(B) activity; however, the slow decay of biofilms under conditions of nutrient limitation reveal its use as an energy-storage molecule to be unlikely. ...[more]
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